FT-FNab08976
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB, IF, IP |
Target | TRIM25 |
Research Area | Epigenetics, Immunology, Metabolism |
Form | liquid |
Recomended Dilution | WB: 1:200-1:2000 |
Type Clonality | polyclonal |
Immunogen | tripartite motif-containing 25 |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | E3 ubiquitin/ISG15 ligase TRIM25|Estrogen-responsive finger protein|RING finger protein 147|RING-type E3 ubiquitin transferase|RING-type E3 ubiquitin transferase TRIM25|Tripartite motif-containing protein 25|Ubiquitin/ISG15-conjugating enzyme TRIM25|Zinc |
Host | Rabbit |
UniProt ID | Q14258 |
Gene ID | 7706 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse |
Observed MW | 71 kDa |
Background | Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for |