FT-FNab07759
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB |
Target | SESN1 |
Research Area | Cardiovascular |
Form | liquid |
Recomended Dilution | WB: 1:500-1:2000 |
Type Clonality | polyclonal |
Immunogen | sestrin 1 |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | Sestrin-1|p53-regulated protein PA26|SESN1|PA26|SEST1 |
Host | Rabbit |
UniProt ID | Q9Y6P5 |
Gene ID | 27244 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse, Rat |
Observed MW | 66-68 kDa |
Background | Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its i |