FT-FNab05371
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB, IHC, IF, FC, IP |
Target | MSH2 |
Research Area | Epigenetics, Metabolism, Cancer, Immunology, Developmental biology |
Form | liquid |
Recomended Dilution | WB: 1:1000-1:4000 |
Type Clonality | polyclonal |
Immunogen | mutS homolog 2, colon cancer, nonpolyposis type 1(E. coli) |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | DNA mismatch repair protein Msh2 (hMSH2)|MutS protein homolog 2|MSH2 |
Host | Rabbit |
UniProt ID | P43246 |
Gene ID | 4436 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse, Rat |
Observed MW | 105 kDa |
Background | Component of the post-replicative DNA mismatch repair system(MMR). Forms two different heterodimers: MutS alpha(MSH2-MSH6 heterodimer) and MutS beta(MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodime |