FT-FNab02401
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB, IF, IHC |
Target | DKK1 |
Research Area | Signal Transduction, Developmental biology |
Form | liquid |
Recomended Dilution | WB: 1:500-1:1000 |
Type Clonality | polyclonal |
Immunogen | dickkopf homolog 1 |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | Dickkopf-related protein 1 (Dickkopf-1, Dkk-1, hDkk-1)|SK|DKK1 |
Host | Rabbit |
UniProt ID | O94907 |
Gene ID | 22943 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse, Rat |
Observed MW | 30-35 kDa |
Background | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they |