ADAM17-Specific antibody View larger

ADAM17-Specific antibody

FT-FNab00139

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Data sheet

Size 100µg
Storage Conditions PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications ELISA, WB
Target ADAM17
Research Area Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience
Form liquid
Recomended Dilution WB: 1:200-1:2000
Type Clonality polyclonal
Immunogen ADAM metallopeptidase domain 17
Minimum Purity ≥95% as determined by SDS-PAGE
Synonyms Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17)|Snake venom-like protease|TNF-alpha convertase|TNF-alpha-converting enzyme|ADAM17|CSVP|TACE
Host Rabbit
UniProt ID P78536
Gene ID 6868
Purification Immunogen affinity purified
Iso type IgG
Reactivity Human
Observed MW 29 kDa
Background The ADAMs(A Disintegrin And Metalloprotease) are multidomain transmembrane proteins. One of the first ADAMs implicated in membrane shedding is ADAM-17, which is shown to release the active form of tumor necrosis factor(TNF)-a from its precursor(PMID:18238

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ADAM17-Specific antibody