ELK-ES9540-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | IHC |
Concentration | 1 mg/ml |
Recomended Dilution | IHC-p 1:50-300 |
Type Clonality | Polyclonal |
Immunogen | Synthesized peptide derived from part region of human protein |
Subcellular Location | Nucleus . Localizes to the promoter regions of several CTNNB1-responsive genes. Also present at known CTCF target sites. . |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 57680 |
Observed Band | 283kD |
Background | This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogene |