ELK-ES8584-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | WB |
Concentration | 1 mg/ml |
Recomended Dilution | WB 1:500-2000, ELISA 1:10000-20000 |
Type Clonality | Polyclonal |
Immunogen | Synthesized phospho-peptide around the phosphorylation site of human MDM2 (Phospho-Tyr394) |
Subcellular Location | Nucleus, nucleoplasm. Cytoplasm . Nucleus, nucleolus. Nucleus . Expressed predominantly in the nucleoplasm. Interaction with ARF(P14) results in the localization of both proteins to the nucleolus. The nucleolar localization signals in both ARF(P14) and MD |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 4193 |
Observed Band | 42kD |
Background | This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpres |