MDM2 (Phospho-Tyr394) Antibody View larger

MDM2 (Phospho-Tyr394) Antibody

ELK-ES8584-100 μL

New product

E3 ubiquitin-protein ligase Mdm2 (EC 6.3.2.-) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (p53-binding protein Mdm2)

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Data sheet

Size 100 μL
Storage Conditions -20°C/1 year
Species Reactivity Cross Human
Applications WB
Concentration 1 mg/ml
Recomended Dilution WB 1:500-2000, ELISA 1:10000-20000
Type Clonality Polyclonal
Immunogen Synthesized phospho-peptide around the phosphorylation site of human MDM2 (Phospho-Tyr394)
Subcellular Location Nucleus, nucleoplasm. Cytoplasm . Nucleus, nucleolus. Nucleus . Expressed predominantly in the nucleoplasm. Interaction with ARF(P14) results in the localization of both proteins to the nucleolus. The nucleolar localization signals in both ARF(P14) and MD
Iso type IgG
Tissue Source Rabbit
Human Gen 4193
Observed Band 42kD
Background This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpres

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MDM2 (Phospho-Tyr394) Antibody