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PTEN rabbit pAb
ELK-ES8470-100 μL
New product
phosphatase and tensin homolog; phosphatase and tensin homolog pseudogene 1
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Data sheet
| Size | 100 μL |
| Storage Conditions | -20°C/1 year |
| Species Reactivity Cross | Human |
| Applications | IF |
| Concentration | 1 mg/ml |
| Recomended Dilution | IF: 1:50-200 IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000 |
| Type Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from PTEN at AA range: 251-300 |
| Subcellular Location | Cytoplasm . Nucleus . Nucleus, PML body . Monoubiquitinated form is nuclear. Nonubiquitinated form is cytoplasmic. Colocalized with PML and USP7 in PML nuclear bodies (PubMed:18716620). XIAP/BIRC4 promotes its nuclear localization (PubMed:19473982). . |
| Iso type | IgG |
| Tissue Source | Rabbit |
| Human Gen | 5728 |
| Observed Band | 50kD |
| Background | This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a cata |
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PTEN rabbit pAb