TLE1/2/3/4 rabbit pAb View larger

TLE1/2/3/4 rabbit pAb

ELK-ES8464-100 μL

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similar to transducin-like enhancer of split 1/2/3/4

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Data sheet

Size 100 μL
Storage Conditions -20°C/1 year
Species Reactivity Cross Human
Applications WB
Concentration 1 mg/ml
Recomended Dilution WB 1:500-2000
Type Clonality Polyclonal
Immunogen The antiserum was produced against synthesized peptide derived from the C-terminal region of human TLE1/TLE2/TLE3/TLE4. AA range:721-770
Subcellular Location Nucleus . Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components.
Iso type IgG
Tissue Source Rabbit
Human Gen 7088
Observed Band 90kD
Background function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effe

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TLE1/2/3/4 rabbit pAb