ELK-ES8464-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | WB |
Concentration | 1 mg/ml |
Recomended Dilution | WB 1:500-2000 |
Type Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized peptide derived from the C-terminal region of human TLE1/TLE2/TLE3/TLE4. AA range:721-770 |
Subcellular Location | Nucleus . Nuclear and chromatin-associated, depending on isoforms and phosphorylation status. Hyperphosphorylation decreases the affinity for nuclear components. |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 7088 |
Observed Band | 90kD |
Background | function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effe |