ELK-ES18299-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | WB |
Concentration | 1 mg/ml |
Recomended Dilution | WB 1:500-2000 |
Type Clonality | Polyclonal |
Immunogen | Synthesized peptide derived from human APEX2 AA range: 196-246 |
Subcellular Location | Nucleus. Cytoplasm. Mitochondrion . Together with PCNA, is redistributed in discrete nuclear foci in presence of oxidative DNA damaging agents. |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 27301 |
Background | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so |