ELK-ES17975-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | WB |
Concentration | 1 mg/ml |
Recomended Dilution | WB 1:1000-2000 |
Type Clonality | Polyclonal |
Immunogen | Synthesized phosho peptide around human BMAL1 (Ser42) |
Subcellular Location | Nucleus . Cytoplasm . Nucleus, PML body . Shuttles between the nucleus and the cytoplasm and this nucleocytoplasmic shuttling is essential for the nuclear accumulation of CLOCK, target gene transcription and the degradation of the CLOCK-ARNTL/BMAL1 hetero |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 406 |
Observed Band | 69kD |
Background | The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription |