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Smad2 (phospho-Ser465/467) rabbit pAb
ELK-ES13077-100 μL
New product
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (JV18-1) (Mad-related protein 2) (hMAD-2) (SMAD family member 2) (SMAD 2) (Smad2) (hSMAD2)
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Data sheet
| Size | 100 μL |
| Storage Conditions | -20°C/1 year |
| Species Reactivity Cross | Human |
| Applications | WB |
| Concentration | 1 mg/ml |
| Recomended Dilution | WB 1:500-2000 |
| Type Clonality | Polyclonal |
| Immunogen | Synthesized phosho peptide around human Smad2 (Ser465 and 467) |
| Subcellular Location | Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD |
| Iso type | IgG |
| Tissue Source | Rabbit |
| Human Gen | 4087 |
| Observed Band | 58kD |
| Background | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional mo |
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Smad2 (phospho-Ser465/467) rabbit pAb