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Smad2/3 (Acetyl-Lys19) rabbit pAb
ELK-ES13074-100 μL
New product
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Data sheet
| Size | 100 μL |
| Storage Conditions | -20°C/1 year |
| Species Reactivity Cross | Human |
| Applications | IHC |
| Concentration | 1 mg/ml |
| Recomended Dilution | IHC-p 1:50-200, WB 1:500-2000 |
| Type Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human Smad2/3 (Acetyl-Lys19) |
| Subcellular Location | Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:9865696, PubMed:21145499). On dephosphorylation by phosphatase PPM1A, released from the SMAD2/SMAD |
| Iso type | IgG |
| Tissue Source | Rabbit |
| Human Gen | 4088/4087 |
| Observed Band | 60kD |
| Background | The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional mo |
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Smad2/3 (Acetyl-Lys19) rabbit pAb