Smad3 (phospho-Ser423/425)  rabbit pAb View larger

Smad3 (phospho-Ser423/425) rabbit pAb

ELK-ES13073-100 μL

New product

Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)

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Data sheet

Size 100 μL
Storage Conditions -20°C/1 year
Species Reactivity Cross Human
Applications WB
Concentration 1 mg/ml
Recomended Dilution WB 1:500-2000
Type Clonality Polyclonal
Immunogen Synthesized phosho peptide around human Smad3 (Ser423 and 425)
Subcellular Location Cytoplasm . Nucleus . Cytoplasmic and nuclear in the absence of TGF-beta. On TGF-beta stimulation, migrates to the nucleus when complexed with SMAD4 (PubMed:15799969, PubMed:21145499). Through the action of the phosphatase PPM1A, released from the SMAD2/S
Iso type IgG
Tissue Source Rabbit
Human Gen 4088
Observed Band 50kD
Background The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional mo

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Smad3 (phospho-Ser423/425) rabbit pAb