ELK-ES10871-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | WB |
Concentration | 1 mg/ml |
Recomended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Type Clonality | Polyclonal |
Immunogen | Synthesized peptide derived from part region of human protein. AA range 655-675 |
Subcellular Location | Late endosome . Lysosome . Cytoplasmic vesicle, autophagosome . Early endosome . Endoplasmic reticulum . Midbody . Chromosome, centromere . Colocalizes with RAB9-positive compartments involved in retrograde transport from late endosomes to trans-Golgi net |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 7405 |
Observed Band | 76kD |
Background | This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity o |