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NFκB-p65 (Mono Methyl Lys314/Lys315) rabbit pAb
ELK-ES1084-100 μL
New product
RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
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Data sheet
| Size | 100 μL |
| Storage Conditions | -20°C/1 year |
| Species Reactivity Cross | Human |
| Applications | WB |
| Concentration | 1 mg/ml |
| Recomended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Type Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human p65 around the mono-methylation site of K314/K315. |
| Subcellular Location | Nucleus . Cytoplasm . Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B) (PubMed:1493333). Colocalized with DDX1 in the nucleus upon TNF-alpha induction (PubMed:19058135). Colocalizes with GFI1 in the nucleu |
| Iso type | IgG |
| Tissue Source | Rabbit |
| Human Gen | 5970 |
| Observed Band | 60kD |
| Background | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcripti |
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NFκB-p65 (Mono Methyl Lys314/Lys315) rabbit pAb