ALKB3 rabbit pAb View larger

ALKB3 rabbit pAb

ELK-ES10629-100 μL

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Data sheet

Size 100 μL
Storage Conditions -20°C/1 year
Species Reactivity Cross Human
Applications WB
Concentration 1 mg/ml
Recomended Dilution WB 1:500-2000 ELISA 1:5000-20000
Type Clonality Polyclonal
Immunogen Synthesized peptide derived from human protein . at AA range: 110-190
Subcellular Location Nucleus . Cytoplasm . Colocalizes with ASCC2 and ASCC3 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage (PubMed:29144457). Predominantly localizes to the nucleus. .
Iso type IgG
Tissue Source Rabbit
Human Gen 221120
Observed Band 31kD
Background The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methy

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ALKB3 rabbit pAb