ELK-ES10425-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | WB |
Concentration | 1 mg/ml |
Recomended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Type Clonality | Polyclonal |
Immunogen | Synthesized peptide derived from human protein . at AA range: 150-230 |
Subcellular Location | Cytoplasm . Nucleus . Mainly nuclear. Binds to chromatin. Localizes to the cytoplasm when monoubiquitinated by the E2/E3 hybrid ubiquitin-protein ligase UBE2O (PubMed:24703950). . |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 8314 |
Observed Band | 80kD |
Background | This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING fin |