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Cleaved-Lamin A (D230) rabbit pAb
ELK-ES1041-100 μL
New product
LMNA; LMN1; Prelamin-A/C
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Data sheet
| Size | 100 μL |
| Storage Conditions | -20°C/1 year |
| Species Reactivity Cross | Human |
| Applications | WB |
| Concentration | 1 mg/ml |
| Recomended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Type Clonality | Polyclonal |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Lamin A. AA range:181-230 |
| Subcellular Location | Nucleus . Nucleus envelope . Nucleus lamina. Nucleus, nucleoplasm. Nucleus matrix . Farnesylation of prelamin-A/C facilitates nuclear envelope targeting and subsequent cleavage by ZMPSTE24/FACE1 to remove the farnesyl group produces mature lamin-A/C, whic |
| Iso type | IgG |
| Tissue Source | Rabbit |
| Human Gen | 4000 |
| Observed Band | 28+75kD |
| Background | lamin A/C(LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lami |
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Cleaved-Lamin A (D230) rabbit pAb