MLKL (8H7) Mouse mAb View larger

MLKL (8H7) Mouse mAb

ELK-EM1328-100 μL

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Mixed lineage kinase domain like protein, FLJ34389

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Data sheet

Size 100 μL
Storage Conditions PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Species Reactivity Cross Human
Applications IHC
Concentration 1mg/mL
Recomended Dilution IHC 1:100-200
Type Clonality Monoclonal
Immunogen Synthetic Peptide
Subcellular Location Cell membrane, Cytoplasm, Membrane
Iso type IgG1
Tissue Source Mouse
Human Gen 197259
Observed Band 54kDa
Background Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr

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MLKL (8H7) Mouse mAb