ELK-ES8533-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | WB |
Concentration | 1 mg/ml |
Recomended Dilution | IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000 |
Type Clonality | Polyclonal |
Immunogen | Synthetic peptide from human protein at AA range: 901-950 |
Subcellular Location | Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cell membrane . Localizes to the plasma membrane (By similarity). According to PubMed:15048887, it is mitochondrial, however such localization remains u |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 57534 |
Observed Band | 130kD |
Background | This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their en |