ELK-ES10054-100 μL
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Size | 100 μL |
Storage Conditions | -20°C/1 year |
Species Reactivity Cross | Human |
Applications | IHC |
Concentration | 1 mg/ml |
Recomended Dilution | IHC-p 1:50-300 |
Type Clonality | Polyclonal |
Immunogen | Synthesized peptide derived from human protein . at AA range: 1280-1360 |
Subcellular Location | Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. . |
Iso type | IgG |
Tissue Source | Rabbit |
Human Gen | 259282 |
Observed Band | 335kD |
Background | Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombino |