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MLKL (8H7) Mouse mAb
ELK-EM1328-100 μL
Producto nuevo
Mixed lineage kinase domain like protein, FLJ34389
Comprando este producto generará 2 Biopuntos. Su cesta contiene un total 2 Biopuntos puede ser convertido en un Biobonos Descuento 8.00EUR.
Hoja técnica
| Size | 100 μL |
| Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Species Reactivity Cross | Human |
| Applications | IHC |
| Concentration | 1mg/mL |
| Recomended Dilution | IHC 1:100-200 |
| Type Clonality | Monoclonal |
| Immunogen | Synthetic Peptide |
| Subcellular Location | Cell membrane, Cytoplasm, Membrane |
| Iso type | IgG1 |
| Tissue Source | Mouse |
| Human Gen | 197259 |
| Observed Band | 54kDa |
| Background | Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr |
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MLKL (8H7) Mouse mAb